The Italian cosmetic take its roots in the history of human custom until they reach the Roman Empire era, improving and evolving to real science in medieval times thanks to religious people that, inventing "the garden of the simple", put the first plug of modern "Erboristeria", flowing then into Renaissance, where characters like Caterina dei Medici, guessing the enormous potential of the olfactory combination linked to what we might define the first "empirical" creams produced by her trusted "speziali", threw the bases of modern cosmetics art.